CACNG1 - Voltage-dependent calcium channel gamma-1 subunit - human protein (Function)
 
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CACNG1 »  Voltage-dependent calcium channel gamma-1 subunit
 
Protein also known as:  Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma.
Gene name:  CACNG1
Family name: PMP-22/EMP/MP20 » CACNG
Entry whose protein(s) existence is based on evidence at transcript level
extend overview
1 11 1
GENE REF ISO

Function

 show evidences
Overview 
This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the ca(+) channel auxiliary subunit 1-8 (cca) family  8.A.16.1.1  
GO molecular function 
Voltage-gated calcium channel activitydefinition[GO:0005245] silver  
  • IEAOrtholog Compara
GO biological process 
Muscle contractiondefinition[GO:0006936]  
1
  • TASPINC
Sarcoplasmic reticulum calcium ion transportdefinition[GO:0070296] silver  
  • IEAOrtholog Compara
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Arrhythmogenic right ventricular cardiomyopathy (ARVC)  hsa05412+786  
Cardiac muscle contraction  hsa04260+786  
Dilated cardiomyopathy  hsa05414+786  
Hypertrophic cardiomyopathy (HCM)  hsa05410+786  
MAPK signaling pathway  hsa04010+786  
 

Keywords

Biological process 
Calcium transport  definition   [KW-0109]
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Molecular function 
Calcium channel  definition   [KW-0107]
Ion channel  definition   [KW-0407]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CACNG1
GenomeRNAi: 786
PRO: PR:Q06432