SLC34A1 - Sodium-dependent phosphate transport protein 2A - human protein (Function)
 
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SLC34A1 »  Sodium-dependent phosphate transport protein 2A  (Sodium-phosphate transport protein 2A)
 
Protein also known as:  Na(+)-dependent phosphate cotransporter 2A.
Gene name:  SLC34A1
Family name: SLC34A transporter
Entry whose protein(s) existence is based on evidence at protein level
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1 39 2
GENE REF ISO

Function

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Overview 
May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the phosphate:na(+) symporter (pnas) family  2.A.58.1.5  
GO molecular function 
PDZ domain bindingdefinition[GO:0030165] silver  
  • IEAOrtholog Compara
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
Protein complex bindingdefinition[GO:0032403] silver  
  • IEAOrtholog Compara
Protein homodimerization activitydefinition[GO:0042803] silver  
  • IEAOrtholog Compara
Sodium-dependent phosphate transmembrane transporter activitydefinition[GO:0015321]  
3
  • IDAUniProtKB
Symporter activitydefinition[GO:0015293]  
  • IEAUniProtKB KW
GO biological process 
Arsenate ion transmembrane transportdefinition[GO:1901684] silver  
  • IEAOrtholog Compara
Bone remodelingdefinition[GO:0046849] silver  
  • IEAOrtholog Compara
Cellular response to metal iondefinition[GO:0071248] silver  
  • IEAOrtholog Compara
Cellular response to parathyroid hormone stimulusdefinition[GO:0071374] silver  
  • IEAOrtholog Compara
Cellular response to staurosporinedefinition[GO:0072734] silver  
  • IEAOrtholog Compara
Dentinogenesisdefinition[GO:0097187] silver  
  • IEAOrtholog Compara
Gentamycin metabolic processdefinition[GO:1901128] silver  
  • IEAOrtholog Compara
Glycoprotein metabolic processdefinition[GO:0009100] silver  
  • IEAOrtholog Compara
Indole metabolic processdefinition[GO:0042431] silver  
  • IEAOrtholog Compara
Kidney developmentdefinition[GO:0001822] silver  
  • IEAOrtholog Compara
Ossificationdefinition[GO:0001503] silver  
  • IEAOrtholog Compara
Phosphate ion homeostasisdefinition[GO:0055062]  
3
  • IDAUniProtKB
Phosphate ion transmembrane transportdefinition[GO:0035435]  
3
  • IDAGOC
Phosphate ion transportdefinition[GO:0006817]  
3
  • IDAUniProtKB
Positive regulation of membrane potentialdefinition[GO:0045838] silver  
  • IEAOrtholog Compara
Positive regulation of phosphate transmembrane transportdefinition[GO:2000187] silver  
  • IEAOrtholog Compara
Positive regulation of sodium-dependent phosphate transportdefinition[GO:2000120] silver  
  • IEAOrtholog Compara
Protein homooligomerizationdefinition[GO:0051260] silver  
  • IEAOrtholog Compara
Response to cadmium iondefinition[GO:0046686]  
1
  • IDAUniProtKB
Response to drugdefinition[GO:0042493] silver  
  • IEAOrtholog Compara
Response to estradioldefinition[GO:0032355] silver  
  • IEAOrtholog Compara
Response to growth hormonedefinition[GO:0060416] silver  
  • IEAOrtholog Compara
Response to lead iondefinition[GO:0010288]  
1
  • IDAUniProtKB
Response to magnesium iondefinition[GO:0032026] silver  
  • IEAOrtholog Compara
Response to mercury iondefinition[GO:0046689]  
1
  • IDAUniProtKB
Response to potassium iondefinition[GO:0035864] silver  
  • IEAOrtholog Compara
Response to thyroid hormonedefinition[GO:0097066] silver  
  • IEAOrtholog Compara
Response to vitamin Adefinition[GO:0033189] silver  
  • IEAOrtholog Compara
Sodium ion transportdefinition[GO:0006814]  
  • IEAUniProtKB KW
Tricarboxylic acid metabolic processdefinition[GO:0072350] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Sodium transport  definition   [KW-0739]
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links