DLX2 - Homeobox protein DLX-2 - human protein (Function)
 
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DLX2 »  Homeobox protein DLX-2
 
Gene name:  DLX2
Family name: Distal-less homeobox
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis.  
1
  • UniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682] silver  
1
  • Ortholog Compara
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
1
  • InterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
1
  • PINC
Single-stranded RNA bindingdefinition[GO:0003727] silver  
1
  • Ortholog Compara
GO biological process 
Brain developmentdefinition[GO:0007420]  
1
  • PINC
Branching morphogenesis of a nervedefinition[GO:0048755] silver  
1
  • Ortholog Compara
Cartilage developmentdefinition[GO:0051216] silver  
1
  • Ortholog Compara
Cerebral cortex GABAergic interneuron fate commitmentdefinition[GO:0021893] silver  
1
  • Ortholog Compara
Embryonic cranial skeleton morphogenesisdefinition[GO:0048701] silver  
1
  • Ortholog Compara
Hippocampus developmentdefinition[GO:0021766] silver  
1
  • Ortholog Compara
Negative regulation of Notch signaling pathwaydefinition[GO:0045746] silver  
1
  • Ortholog Compara
Negative regulation of oligodendrocyte differentiationdefinition[GO:0048715] silver  
1
  • Ortholog Compara
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122] silver  
1
  • Ortholog Compara
Odontogenesis of dentin-containing toothdefinition[GO:0042475] silver  
1
  • Ortholog Compara
Olfactory bulb developmentdefinition[GO:0021772] silver  
1
  • Ortholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
1
  • Ortholog Compara
Proximal/distal pattern formationdefinition[GO:0009954] silver  
1
  • Ortholog Compara
Regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitmentdefinition[GO:0021882] silver  
1
  • Ortholog Compara
Subpallium developmentdefinition[GO:0021544] silver  
1
  • Ortholog Compara
 

Keywords

Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: DLX2
GenomeRNAi: 1746
PRO: PR:Q07687