SLC3A1 - Neutral and basic amino acid transport protein rBAT - human protein (Function)
 
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SLC3A1 »  Neutral and basic amino acid transport protein rBAT  (NBAT)
 
Protein also known as:  B(0,+)-type amino acid transport protein.
Gene name:  SLC3A1
Entry whose protein(s) existence is based on evidence at protein level
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1 53 1
GENE REF ISO

Function

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Overview 
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule.  
4
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the rbat transport accessory protein (rbat) family  8.A.9.1.2  
GO molecular function 
Amino acid transmembrane transporter activitydefinition[GO:0015171]  
1
  • TASPINC
Basic amino acid transmembrane transporter activitydefinition[GO:0015174]  
1
  • TASPINC
Catalytic activitydefinition[GO:0003824] silver  
  • IEAInterPro 2 GO
Cation bindingdefinition[GO:0043169] silver  
  • IEAInterPro 2 GO
L-cystine transmembrane transporter activitydefinition[GO:0015184]  
1
  • TASPINC
Protein heterodimerization activitydefinition[GO:0046982] silver  
  • IEAOrtholog Compara
GO biological process 
Amino acid transmembrane transportdefinition[GO:0003333]  
2
  • TASGOC
Basic amino acid transportdefinition[GO:0015802]  
1
  • TASPINC
Carbohydrate metabolic processdefinition[GO:0005975] silver  
  • IEAInterPro 2 GO
Cellular amino acid metabolic processdefinition[GO:0006520]  
1
  • TASPINC
Ion transmembrane transportdefinition[GO:0034220]  
2
  • TASGOC
L-alpha-amino acid transmembrane transportdefinition[GO:1902475]  
1
  • TASGOC
L-cystine transportdefinition[GO:0015811]  
1
  • TASPINC
Enzymatic activity 
According to CAZy, this protein is belongs to the following pathway:
Glycoside Hydrolase Family 13  GH13  
Pathways 
According to KEGG, this protein belongs to the following pathway:
Protein digestion and absorption  hsa04974+6519  
According to Reactome, this protein belongs to the following pathways:
Amino acid and oligopeptide SLC transporters  REACT_19419  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Amino-acid transport  definition   [KW-0029]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SLC3A1
GenomeRNAi: 6519
PRO: PR:Q07837