KCNA1 - Potassium voltage-gated channel subfamily A member 1 - human protein (Function)
 
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Protein
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References

 
KCNA1 »  Potassium voltage-gated channel subfamily A member 1
 
Protein also known as:  Voltage-gated potassium channel subunit Kv1.1.
Gene name:  KCNA1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 56 1
GENE REF ISO

Function

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Overview 
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the voltage-gated ion channel (vic) superfamily  1.A.1.2.12  
GO molecular function 
Delayed rectifier potassium channel activitydefinition[GO:0005251] silver  
  • IBARefGenome
Potassium channel activitydefinition[GO:0005267]  
1
  • TASPINC
Potassium ion transmembrane transporter activitydefinition[GO:0015079]  
1
  • TASPINC
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Potassium ion transportdefinition[GO:0006813]  
1
  • TASPINC
Protein homooligomerizationdefinition[GO:0051260] silver  
  • IEAInterPro 2 GO
Pathways 
According to Reactome, this protein belongs to the following pathway:
Neuronal System  REACT_13685  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Kv1.1
GenomeRNAi: 3736
PRO: PR:Q09470
Chemistry
GuidetoPHARMACOLOGY: 538