ARHGEF5 - Rho guanine nucleotide exchange factor 5 - human protein (Function)
 
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ARHGEF5 »  Rho guanine nucleotide exchange factor 5
 
Protein also known as:  Transforming immortalized mammary oncogene.
Gene name:  ARHGEF5
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
GTP bindingdefinition[GO:0005525]  
1
  • TASPINC
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
Rho guanyl-nucleotide exchange factor activitydefinition[GO:0005089] silver  
  • IEAInterPro 2 GO
GO biological process 
Actin cytoskeleton organizationdefinition[GO:0030036] silver  
  • IEAOrtholog Compara
Intracellular signal transductiondefinition[GO:0035556] silver  
  • IEAInterPro 2 GO
Myeloid dendritic cell chemotaxisdefinition[GO:0002408] silver  
  • IEAOrtholog Compara
Positive regulation of podosome assemblydefinition[GO:0071803] silver  
  • IEAOrtholog Compara
Positive regulation of Rho GTPase activitydefinition[GO:0032321] silver  
  • IEAOrtholog Compara
Regulation of Rho GTPase activitydefinition[GO:0032319]  
1
  • IDAMGI
 

Keywords

Molecular function 
Guanine-nucleotide releasing factor  definition   [KW-0344]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ARHGEF5
GenomeRNAi: 7984
PRO: PR:Q12774