POU4F2 - POU domain, class 4, transcription factor 2 - human protein (Function)
 
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POU4F2 »  POU domain, class 4, transcription factor 2
 
Protein also known as:  Brain-specific homeobox/POU domain protein 3B (Brn-3B).
Gene name:  POU4F2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons.  
  • CuratedUniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682] silver  
  • IEAOrtholog Compara
RNA polymerase II core promoter proximal region sequence-specific DNA bindingdefinition[GO:0000978]  
1
  • IDAUniProtKB
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptiondefinition[GO:0001078]  
  • ISSOrtholog Curator
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001077]  
1
  • IDAUniProtKB
GO biological process 
Axon extensiondefinition[GO:0048675] silver  
  • IEAOrtholog Compara
Axon guidancedefinition[GO:0007411]  
  • ISSOrtholog Curator
Intracellular estrogen receptor signaling pathwaydefinition[GO:0030520]  
1
  • IDAUniProtKB
MAPK cascadedefinition[GO:0000165]  
1
  • IDAUniProtKB
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122]  
  • ISSOrtholog Curator
Neuromuscular process controlling balancedefinition[GO:0050885] silver  
  • IEAOrtholog Compara
Neuron differentiationdefinition[GO:0030182]  
  • ISSOrtholog Curator
Positive regulation of cell differentiationdefinition[GO:0045597]  
  • ISSOrtholog Curator
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
1
  • IDAUniProtKB
Retina development in camera-type eyedefinition[GO:0060041]  
  • ISSOrtholog Curator
Retinal ganglion cell axon guidancedefinition[GO:0031290] silver  
  • IEAOrtholog Compara
Sensory perception of sounddefinition[GO:0007605] silver  
  • IEAOrtholog Compara
Transcription from RNA polymerase II promoterdefinition[GO:0006366]  
1
  • IDAGOC
  • ISSOrtholog Curator
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: POU4F2
GenomeRNAi: 5458
PRO: PR:Q12837