COX10 - Protoheme IX farnesyltransferase, mitochondrial - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
COX10 »  Protoheme IX farnesyltransferase, mitochondrial   [ EC 2.5.1.- ]
 
Protein also known as:  Heme O synthase.
Gene name:  COX10
Family name: UbiA prenyltransferase
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 20 1
GENE REF ISO

Function

 show evidences
Overview 
Converts protoheme IX and farnesyl diphosphate to heme O (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Contributes to cytochrome-c oxidase activitydefinition[GO:0004129]  
1
  • IMPHGNC
Farnesyltranstransferase activitydefinition[GO:0004311]  
1
  • TASPINC
Protoheme IX farnesyltransferase activitydefinition[GO:0008495] silver  
  • IEAInterPro 2 GO
GO biological process 
Aerobic respirationdefinition[GO:0009060] silver  
  • IEAOrtholog Compara
Cellular respirationdefinition[GO:0045333]  
1
  • IGIHGNC
Heme a biosynthetic processdefinition[GO:0006784]  
1
  • IMPHGNC
Heme O biosynthetic processdefinition[GO:0048034] silver  
  • IEAInterPro 2 GO
Hydrogen ion transmembrane transportdefinition[GO:1902600]  
1
  • IMPGOC
Mitochondrial electron transport, cytochrome c to oxygendefinition[GO:0006123]  
1
  • ICHGNC
Mitochondrial fissiondefinition[GO:0000266] silver  
  • IEAOrtholog Compara
Respiratory chain complex IV assemblydefinition[GO:0008535]  
1
  • IMPHGNC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Metabolic pathways  hsa01100+1352  
Oxidative phosphorylation  hsa00190+1352  
Porphyrin and chlorophyll metabolism  hsa00860+1352  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Biological process 
Heme biosynthesis  definition   [KW-0350]
Molecular function 
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: COX10
GenomeRNAi: 1352
PRO: PR:Q12887