SLC14A1 - Urea transporter 1 - human protein (Function)
 
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Protein
Gene
References

 
SLC14A1 »  Urea transporter 1
 
Protein also known as:  Solute carrier family 14 member 1.
Gene name:  SLC14A1
Entry whose protein(s) existence is based on evidence at protein level
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1 39 2
GENE REF ISO

Function

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Overview 
Mediates urea transport in erythrocytes (By similarity). Low-affinity facilitative urea transporter that allow rapid equilibration between the urinary space and the hyperosmotic interstitium. The rate of urea conduction is increased by hypoosmotic stress.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the urea transporter (ut) family  1.A.28.1.5  
GO molecular function 
Urea transmembrane transporter activitydefinition[GO:0015204] silver  
  • IEAOrtholog Compara
Water transmembrane transporter activitydefinition[GO:0005372] silver  
  • IEAOrtholog Compara
GO biological process 
Urea transportdefinition[GO:0015840]  
1
  • TASPINC
Pathways 
According to Reactome, this protein belongs to the following pathways:
Amine compound SLC transporters  REACT_20679  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Molecular function 
Blood group antigen  definition   [KW-0095]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SLC14A1
GenomeRNAi: 6563
PRO: PR:Q13336