AQP6 - Aquaporin-6 - human protein (Function)
 
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Protein
Gene
References

 
AQP6 »  Aquaporin-6  (AQP-6)
 
Protein also known as:  Kidney-specific aquaporin.
Gene name:  AQP6
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.  
1
  • UniProtKB
According to TCDB this is a transporter from family:
the major intrinsic protein (mip) family  1.A.8.8.4  
GO molecular function 
Glycerol channel activitydefinition[GO:0015254]  
1
  • RefGenome
Nitrate transmembrane transporter activitydefinition[GO:0015112] silver  
1
  • Ortholog Compara
Water channel activitydefinition[GO:0015250]  
1
  • PINC
GO biological process 
Cellular water homeostasisdefinition[GO:0009992]  
1
  • RefGenome
Excretiondefinition[GO:0007588]  
1
  • PINC
Glycerol transportdefinition[GO:0015793]  
1
  • RefGenome
Ion transmembrane transportdefinition[GO:0034220]  
1
  • RefGenome
Nitrate transportdefinition[GO:0015706] silver  
1
  • Ortholog Compara
Odontogenesisdefinition[GO:0042476]  
1
  • UniProtKB
Transportdefinition[GO:0006810]  
1
  • PINC
Pathways 
According to Reactome, this protein belongs to the following pathway:
Passive transport by Aquaporins  REACT_23826  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: AQP6
GenomeRNAi: 363
PRO: PR:Q13520
Chemistry
GuidetoPHARMACOLOGY: 693