PEX6 - Peroxisome assembly factor 2 - human protein (Function)
 
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Protein
Gene
References

 
PEX6 »  Peroxisome assembly factor 2  (PAF-2)
 
Protein also known as:  Peroxisomal biogenesis factor 6.
Gene name:  PEX6
Family name: AAA ATPase
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 33 1
GENE REF ISO

Function

 show evidences
Overview 
Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the peroxisomal protein importer (ppi) family  3.A.20.1.1  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • IMPUniProtKB
ATPase activitydefinition[GO:0016887]  
1
  • IMPUniProtKB
ATPase activity, coupleddefinition[GO:0042623]  
1
  • IMPUniProtKB
Protein bindingdefinition[GO:0005515]  
3
  • IPIUniProtKB
  • IPIIntAct
Protein C-terminus bindingdefinition[GO:0008022]  
1
  • IPIUniProtKB
Protein complex bindingdefinition[GO:0032403]  
1
  • IDAUniProtKB
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
2
  • IMPGOC
Peroxisome organizationdefinition[GO:0007031]  
1
  • IMPUniProtKB
Protein import into peroxisome matrix, translocationdefinition[GO:0016561]  
1
  • IMPUniProtKB
Protein stabilizationdefinition[GO:0050821]  
1
  • IMPUniProtKB
Protein targeting to peroxisomedefinition[GO:0006625]  
1
  • IMPUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Peroxisome  hsa04146+5190  
 

Keywords

Biological process 
Peroxisome biogenesis  definition   [KW-0962]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PEX6
GenomeRNAi: 5190
PRO: PR:Q13608