RAPSN - 43 kDa receptor-associated protein of the synapse - human protein (Function)
 
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RAPSN »  43 kDa receptor-associated protein of the synapse  (RAPsyn)
 
Protein also known as:  Acetylcholine receptor-associated 43 kDa protein.
Gene name:  RAPSN
Family name: RAPsyn
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 33 2
GENE REF ISO

Function

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Overview 
Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.  
1
  • UniProtKB
GO molecular function 
Acetylcholine receptor bindingdefinition[GO:0033130]  
1
  • MGI
Ionotropic glutamate receptor bindingdefinition[GO:0035255] silver  
1
  • Ortholog Compara
Protein anchordefinition[GO:0043495] silver  
1
  • Ortholog Compara
Zinc ion bindingdefinition[GO:0008270] silver  
1
  • InterPro 2 GO
GO biological process 
Positive regulation of neuromuscular synaptic transmissiondefinition[GO:1900075] silver  
1
  • Ortholog Compara
Positive regulation of neuron apoptotic processdefinition[GO:0043525] silver  
1
  • Ortholog Compara
Regulation of postsynaptic membrane organizationdefinition[GO:1901626] silver  
1
  • Ortholog Compara
Skeletal muscle acetylcholine-gated channel clusteringdefinition[GO:0071340] silver  
1
  • Ortholog Compara
Synaptic transmissiondefinition[GO:0007268]  
1
  • PINC
Synaptic transmission, cholinergicdefinition[GO:0007271]  
1
  • MGI
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: RAPSN
GenomeRNAi: 5913
PRO: PR:Q13702