ALCAM - CD166 antigen - human protein (Function)
 
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ALCAM »  CD166 antigen
 
Protein also known as:  Activated leukocyte cell adhesion molecule; CD antigen CD166.
Gene name:  ALCAM
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.  
  • CuratedUniProtKB
GO molecular function 
Receptor bindingdefinition[GO:0005102]  
1
  • TASPINC
GO biological process 
Cell adhesiondefinition[GO:0007155]  
  • IEAUniProtKB KW
Motor neuron axon guidancedefinition[GO:0008045] silver  
  • IEAOrtholog Compara
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Enzymatic activity 
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathway:
Cell adhesion molecules (CAMs)  hsa04514+214  
According to Reactome, this protein belongs to the following pathway:
Developmental Biology  REACT_111045  
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ALCAM
GenomeRNAi: 214
PRO: PR:Q13740