LAMB3 - Laminin subunit beta-3 - human protein (Function)
 
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Protein
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References

 
LAMB3 »  Laminin subunit beta-3
 
Gene name:  LAMB3
Entry whose protein(s) existence is based on evidence at protein level
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1 67 1
GENE REF ISO

Function

 show evidences
Overview 
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.  
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Protein complex bindingdefinition[GO:0032403] silver  
  • IEAOrtholog Compara
Structural molecule activitydefinition[GO:0005198]  
1
  • NASPINC
GO biological process 
Brown fat cell differentiationdefinition[GO:0050873] silver  
  • IEAOrtholog Compara
Cell adhesiondefinition[GO:0007155]  
  • IEAUniProtKB KW
Epidermis developmentdefinition[GO:0008544]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Amoebiasis  hsa05146+3914  
ECM-receptor interaction  hsa04512+3914  
Focal adhesion  hsa04510+3914  
Pathways in cancer  hsa05200+3914  
Small cell lung cancer  hsa05222+3914  
Toxoplasmosis  hsa05145+3914  
According to Reactome, this protein belongs to the following pathways:
Anchoring fibril formation  REACT_150268  
Assembly of collagen fibrils and other multimeric structures  REACT_150180  
Degradation of the extracellular matrix  REACT_118572  
Laminin interactions  REACT_169262  
Non-integrin membrane-ECM interactions  REACT_163874  
Type I hemidesmosome assembly  REACT_20537  
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Laminin,_beta_3
GenomeRNAi: 3914
PRO: PR:Q13751