APOF - Apolipoprotein F - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
APOF »  Apolipoprotein F  (Apo-F)
 
Protein also known as:  Lipid transfer inhibitor protein (LTIP).
Gene name:  APOF
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 15 1
GENE REF ISO

Function

 show evidences
Overview 
Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.  
1
  • CuratedUniProtKB
GO molecular function 
Cholesterol bindingdefinition[GO:0015485]  
1
  • TASPINC
Lipid transporter activitydefinition[GO:0005319]  
1
  • TASPINC
Receptor bindingdefinition[GO:0005102]  
1
  • TASPINC
GO biological process 
Cholesterol effluxdefinition[GO:0033344] silver  
  • IEAOrtholog Compara
Cholesterol metabolic processdefinition[GO:0008203] silver  
  • IEAOrtholog Compara
Lipid metabolic processdefinition[GO:0006629]  
1
  • TASPINC
Lipid transportdefinition[GO:0006869]  
1
  • TASPINC
Triglyceride metabolic processdefinition[GO:0006641] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
Cholesterol metabolism  definition   [KW-0153]
Lipid metabolism  definition   [KW-0443]
Lipid transport  definition   [KW-0445]
Steroid metabolism  definition   [KW-0753]
Sterol metabolism  definition   [KW-1207]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: APOF
GenomeRNAi: 319
PRO: PR:Q13790