GPR18 - N-arachidonyl glycine receptor - human protein (Function)
 
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Protein
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GPR18 »  N-arachidonyl glycine receptor  (NAGly receptor)
 
Protein also known as:  G-protein coupled receptor 18.
Gene name:  GPR18
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.  
1
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
1
  • NASUniProtKB
GO biological process 
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • NASUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathways:
Class A/1 (Rhodopsin-like receptors)  REACT_14828  
G alpha (i) signalling events  REACT_19231  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: GPR18
GenomeRNAi: 2841
PRO: PR:Q14330
Chemistry
GuidetoPHARMACOLOGY: 89