KCNB1 - Potassium voltage-gated channel subfamily B member 1 - human protein (Function)
 
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Protein
Gene
References

 
KCNB1 »  Potassium voltage-gated channel subfamily B member 1
 
Protein also known as:  Voltage-gated potassium channel subunit Kv2.1.
Gene name:  KCNB1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 46 1
GENE REF ISO

Function

 show evidences
Overview 
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the voltage-gated ion channel (vic) superfamily  1.A.1.2.11  
GO molecular function 
Delayed rectifier potassium channel activitydefinition[GO:0005251] silver  
  • IBARefGenome
Outward rectifier potassium channel activitydefinition[GO:0015271] silver  
  • IEAOrtholog Compara
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
Protein N-terminus bindingdefinition[GO:0047485] silver  
  • IEAOrtholog Compara
GO biological process 
Potassium ion transmembrane transportdefinition[GO:0071805]  
  • IEAUniProtKB KW
Protein homooligomerizationdefinition[GO:0051260] silver  
  • IEAInterPro 2 GO
Regulation of ion transmembrane transportdefinition[GO:0034765]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Taste transduction  hsa04742+3745  
According to Reactome, this protein belongs to the following pathways:
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion  REACT_18274  
Voltage gated Potassium channels  REACT_75770  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: KCNB1
GenomeRNAi: 3745
PRO: PR:Q14721
Chemistry
GuidetoPHARMACOLOGY: 546