ICAM4 - Intercellular adhesion molecule 4 - human protein (Function)
 
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Protein
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ICAM4 »  Intercellular adhesion molecule 4  (ICAM-4)
 
Protein also known as:  Landsteiner-Wiener blood group glycoprotein (LW blood group protein); CD antigen CD242.
Gene name:  ICAM4
Family name: Immunoglobulin » ICAM
Entry whose protein(s) existence is based on evidence at transcript level
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1 30 3
GENE REF ISO

Function

 show evidences
Overview 
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.  
1
  • CuratedUniProtKB
GO molecular function 
Integrin bindingdefinition[GO:0005178]  
1
  • TASPINC
GO biological process 
Cell-cell adhesiondefinition[GO:0016337] silver  
  • IEAInterPro 2 GO
Pathways 
According to Reactome, this protein belongs to the following pathways:
Extracellular matrix organization  REACT_118779  
Immune System  REACT_6900  
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Molecular function 
Blood group antigen  definition   [KW-0095]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 3386
PRO: PR:Q14773