SLC10A1 - Sodium/bile acid cotransporter - human protein (Function)
 
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Protein
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References

 
SLC10A1 »  Sodium/bile acid cotransporter
 
Protein also known as:  Sodium/taurocholate cotransporting polypeptide.
Gene name:  SLC10A1
Entry whose protein(s) existence is based on evidence at transcript level
extend overview
1 27 1
GENE REF ISO

Function

 show evidences
Overview 
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the bile acid:na(+) symporter (bass) family  2.A.28.1.9  
GO molecular function 
Bile acid:sodium symporter activitydefinition[GO:0008508] silver  
  • IEAInterPro 2 GO
GO biological process 
Ion transmembrane transportdefinition[GO:0034220]  
1
  • TASGOC
Lipid transportdefinition[GO:0006869]  
1
  • TASGOC
Sodium ion transmembrane transportdefinition[GO:0035725]  
1
  • TASGOC
Transmembrane transportdefinition[GO:0055085]  
1
  • TASGOC
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Bile secretion  hsa04976+6554  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Sodium transport  definition   [KW-0739]
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: SLC10A1
GenomeRNAi: 6554
PRO: PR:Q14973
Chemistry
GuidetoPHARMACOLOGY: 959