EFTUD2 - 116 kDa U5 small nuclear ribonucleoprotein component - human protein (Function)
 
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Protein
Gene
References

 
EFTUD2 »  116 kDa U5 small nuclear ribonucleoprotein component
 
Protein also known as:  Elongation factor Tu GTP-binding domain-containing protein 2.
Gene name:  EFTUD2
Entry whose protein(s) existence is based on evidence at protein level
extend overview
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GENE REF ISO

Function

 show evidences
Overview 
Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP.  
1
  • UniProtKB
GO molecular function 
GTP bindingdefinition[GO:0005525]  
1
  • UniProtKB KW
GTPase activitydefinition[GO:0003924] silver  
1
  • InterPro 2 GO
Poly(A) RNA bindingdefinition[GO:0044822]  
2
  • UniProtKB
Protein bindingdefinition[GO:0005515]  
5
  • IntAct
  • UniProtKB
GO biological process 
mRNA processingdefinition[GO:0006397]  
1
  • PINC
mRNA splicing, via spliceosomedefinition[GO:0000398]  
1
  • UniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Spliceosome  hsa03040+9343  
According to Reactome, this protein belongs to the following pathways:
mRNA Splicing - Major Pathway  REACT_467  
mRNA Splicing - Minor Pathway  REACT_1753  
 

Keywords

Biological process 
mRNA processing  definition   [KW-0507]
mRNA splicing  definition   [KW-0508]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: EFTUD2
GenomeRNAi: 9343
PRO: PR:Q15029