EIF4H - Eukaryotic translation initiation factor 4H - human protein (Function)
 
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Protein
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References

 
EIF4H »  Eukaryotic translation initiation factor 4H  (eIF-4H)
 
Protein also known as:  Williams-Beuren syndrome chromosomal region 1 protein.
Gene name:  EIF4H
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 40 2
GENE REF ISO

Function

 show evidences
Overview 
Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.  
2
  • CuratedUniProtKB
GO molecular function 
Nucleotide bindingdefinition[GO:0000166] silver  
  • IEAInterPro 2 GO
Poly(A) RNA bindingdefinition[GO:0044822]  
2
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
RNA bindingdefinition[GO:0003723]  
1
  • TASPINC
Translation factor activity, nucleic acid bindingdefinition[GO:0008135]  
1
  • TASPINC
Translation initiation factor activitydefinition[GO:0003743]  
  • IEAUniProtKB KW
GO biological process 
Developmental growthdefinition[GO:0048589] silver  
  • IEAOrtholog Compara
Regulation of translational initiationdefinition[GO:0006446]  
1
  • TASPINC
Sexual reproductiondefinition[GO:0019953] silver  
  • IEAOrtholog Compara
Viral processdefinition[GO:0016032]  
  • IEAUniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathways:
3' -UTR-mediated translational regulation  REACT_1762  
Gene Expression  REACT_71  
Metabolism of proteins  REACT_17015  
 

Keywords

Biological process 
Host-virus interaction  definition   [KW-0945]
Protein biosynthesis  definition   [KW-0648]
Molecular function 
Initiation factor  definition   [KW-0396]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: EIF4H
GenomeRNAi: 7458
PRO: PR:Q15056