KIF14 - Kinesin-like protein KIF14 - human protein (Function)
 
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KIF14 »  Kinesin-like protein KIF14
 
Gene name:  KIF14
Entry whose protein(s) existence is based on evidence at protein level
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1 59 1
GENE REF ISO

Function

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Overview 
Plays an essential role in cytokinesis.  
3
  • UniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • Ortholog Curator
ATPase activitydefinition[GO:0016887]  
2
  • RefGenome
  • Ortholog Curator
Microtubule bindingdefinition[GO:0008017]  
1
  • Ortholog Curator
Microtubule motor activitydefinition[GO:0003777]  
1
  • RefGenome
PDZ domain bindingdefinition[GO:0030165]  
1
  • MGI
Plus-end-directed microtubule motor activitydefinition[GO:0008574]  
1
  • Ortholog Curator
Protein bindingdefinition[GO:0005515]  
3
  • IntAct
  • UniProtKB
Protein kinase bindingdefinition[GO:0019901]  
2
  • UniProtKB
Tubulin bindingdefinition[GO:0015631]  
1
  • Ortholog Curator
GO biological process 
Activation of protein kinase activitydefinition[GO:0032147]  
1
  • UniProtKB
ATP catabolic processdefinition[GO:0006200]  
2
  • RefGenome
  • Ortholog Curator
Cell proliferation in forebraindefinition[GO:0021846]  
1
  • Ortholog Curator
Cerebellar cortex developmentdefinition[GO:0021695]  
1
  • Ortholog Curator
Cerebellar granular layer structural organizationdefinition[GO:0021685]  
1
  • Ortholog Curator
Cerebellar Purkinje cell layer structural organizationdefinition[GO:0021693]  
1
  • Ortholog Curator
Cerebral cortex developmentdefinition[GO:0021987]  
1
  • Ortholog Curator
Cytoskeleton-dependent intracellular transportdefinition[GO:0030705]  
1
  • RefGenome
Establishment of protein localizationdefinition[GO:0045184]  
1
  • MGI
Hippocampus developmentdefinition[GO:0021766]  
1
  • Ortholog Curator
Not  Microtubule depolymerizationdefinition[GO:0007019]  
1
  • Ortholog Curator
Microtubule-based movementdefinition[GO:0007018]  
1
  • RefGenome
Mitotic cell cycle processdefinition[GO:1903047]  
1
  • UniProtKB
Mitotic metaphase plate congressiondefinition[GO:0007080]  
1
  • UniProtKB
Negative regulation of apoptotic processdefinition[GO:0043066]  
1
  • UniProtKB
Negative regulation of integrin activationdefinition[GO:0033624]  
1
  • MGI
Negative regulation of neuron apoptotic processdefinition[GO:0043524]  
1
  • Ortholog Curator
Olfactory bulb developmentdefinition[GO:0021772]  
1
  • Ortholog Curator
Positive regulation of cell proliferationdefinition[GO:0008284]  
2
  • UniProtKB
Positive regulation of cytokinesisdefinition[GO:0032467]  
2
  • UniProtKB
Proteasome-mediated ubiquitin-dependent protein catabolic processdefinition[GO:0043161]  
1
  • UniProtKB
Regulation of cell adhesiondefinition[GO:0030155]  
1
  • MGI
Regulation of cell growthdefinition[GO:0001558]  
1
  • UniProtKB
Regulation of cell migrationdefinition[GO:0030334]  
1
  • MGI
Regulation of G1/S transition of mitotic cell cycledefinition[GO:2000045]  
1
  • UniProtKB
Regulation of G2/M transition of mitotic cell cycledefinition[GO:0010389]  
1
  • UniProtKB
Regulation of myelinationdefinition[GO:0031641]  
1
  • Ortholog Curator
Regulation of neuron apoptotic processdefinition[GO:0043523]  
1
  • Ortholog Curator
Regulation of Rap protein signal transductiondefinition[GO:0032487]  
1
  • MGI
Not  Response to docetaxel trihydratedefinition[GO:1902519]  
1
  • UniProtKB
SCF-dependent proteasomal ubiquitin-dependent protein catabolic processdefinition[GO:0031146]  
1
  • UniProtKB
Substrate adhesion-dependent cell spreadingdefinition[GO:0034446]  
1
  • MGI
 

Keywords

Molecular function 
Motor protein  definition   [KW-0505]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: KIF14
GenomeRNAi: 9928
PRO: PR:Q15058