OXA1L - Mitochondrial inner membrane protein OXA1L - human protein (Function)
 
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OXA1L »  Mitochondrial inner membrane protein OXA1L
 
Protein also known as:  Oxidase assembly 1-like protein (OXA1-like protein).
Gene name:  OXA1L
Family name: OXA1/ALB3/YidC
Entry whose protein(s) existence is based on evidence at protein level
extend overview
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GENE REF ISO

Function

 show evidences
Overview 
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.  
2
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the cytochrome oxidase biogenesis (oxa1) family  2.A.9.1.2  
GO molecular function 
Mitochondrial ribosome bindingdefinition[GO:0097177]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Protein homodimerization activitydefinition[GO:0042803]  
2
  • IDAUniProtKB
GO biological process 
Aerobic respirationdefinition[GO:0009060]  
2
  • NASUniProtKB
Mitochondrial proton-transporting ATP synthase complex assemblydefinition[GO:0033615]  
1
  • IMPUniProtKB
Mitochondrial respiratory chain complex I assemblydefinition[GO:0032981]  
1
  • IMPUniProtKB
Mitochondrial respiratory chain complex I biogenesisdefinition[GO:0097031]  
1
  • IMPUniProtKB
Negative regulation of ATPase activitydefinition[GO:0032780]  
1
  • IMPUniProtKB
Negative regulation of oxidoreductase activitydefinition[GO:0051354]  
1
  • IMPUniProtKB
Oxidation-reduction processdefinition[GO:0055114]  
1
  • NASUniProtKB
Protein complex assemblydefinition[GO:0006461]  
1
  • NASUniProtKB
Protein insertion into membranedefinition[GO:0051205] silver  
  • IEAInterPro 2 GO
Protein tetramerizationdefinition[GO:0051262]  
2
  • IDAUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Protein export  hsa03060+5018  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 5018
PRO: PR:Q15070