OXA1L - Mitochondrial inner membrane protein OXA1L - human protein (Function)
 
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OXA1L »  Mitochondrial inner membrane protein OXA1L
 
Protein also known as:  Oxidase assembly 1-like protein (OXA1-like protein).
Gene name:  OXA1L
Family name: OXA1/ALB3/YidC
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.  
3
  • UniProtKB
According to TCDB this is a transporter from family:
the cytochrome oxidase biogenesis (oxa1) family  2.A.9.1.2  
GO molecular function 
Mitochondrial ribosome bindingdefinition[GO:0097177]  
1
  • UniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • UniProtKB
Protein homodimerization activitydefinition[GO:0042803]  
2
  • UniProtKB
GO biological process 
Aerobic respirationdefinition[GO:0009060]  
2
  • UniProtKB
Mitochondrial proton-transporting ATP synthase complex assemblydefinition[GO:0033615]  
1
  • UniProtKB
Mitochondrial respiratory chain complex I assemblydefinition[GO:0032981]  
1
  • UniProtKB
Mitochondrial respiratory chain complex I biogenesisdefinition[GO:0097031]  
1
  • UniProtKB
Negative regulation of ATPase activitydefinition[GO:0032780]  
1
  • UniProtKB
Negative regulation of oxidoreductase activitydefinition[GO:0051354]  
1
  • UniProtKB
Oxidation-reduction processdefinition[GO:0055114]  
1
  • UniProtKB
Protein complex assemblydefinition[GO:0006461]  
1
  • UniProtKB
Protein insertion into membranedefinition[GO:0051205] silver  
1
  • InterPro 2 GO
Protein tetramerizationdefinition[GO:0051262]  
2
  • UniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Protein export  hsa03060+5018  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 5018
PRO: PR:Q15070