EBP - 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase - human protein (Function)
 
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EBP »  3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase   [ EC 5.3.3.5 ]
 
Protein also known as:  Delta(8)-Delta(7) sterol isomerase (D8-D7 sterol isomerase).
Gene name:  EBP
Family name: EBP
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.  
  • CuratedUniProtKB
GO molecular function 
C-8 sterol isomerase activitydefinition[GO:0000247] silver  
  • IEAOrtholog Compara
Cholestenol delta-isomerase activitydefinition[GO:0047750]  
  • IEAEC 2 GO
Drug transmembrane transporter activitydefinition[GO:0015238]  
1
  • TASPINC
Steroid delta-isomerase activitydefinition[GO:0004769]  
1
  • TASPINC
Transmembrane signaling receptor activitydefinition[GO:0004888]  
1
  • TASPINC
GO biological process 
Cholesterol biosynthetic processdefinition[GO:0006695]  
  • IEAUniPathway
Cholesterol metabolic processdefinition[GO:0008203]  
1
  • TASPINC
Drug transmembrane transportdefinition[GO:0006855]  
1
  • TASGOC
Hemopoiesisdefinition[GO:0030097] silver  
  • IEAOrtholog Compara
Signal transductiondefinition[GO:0007165]  
1
  • TASGOC
Skeletal system developmentdefinition[GO:0001501]  
1
  • TASPINC
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 5.3.3.5: 5-alpha-cholest-7-en-3-beta-ol 5-alpha-cholest-8-en-3-beta-ol.  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Metabolic pathways  hsa01100+10682  
Steroid biosynthesis  hsa00100+10682  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 
More information is available from:
 

Keywords

Biological process 
Cholesterol biosynthesis  definition   [KW-0152]
Cholesterol metabolism  definition   [KW-0153]
Lipid biosynthesis  definition   [KW-0444]
Lipid metabolism  definition   [KW-0443]
Steroid biosynthesis  definition   [KW-0752]
Steroid metabolism  definition   [KW-0753]
Sterol biosynthesis  definition   [KW-0756]
Sterol metabolism  definition   [KW-1207]
Molecular function 
Isomerase  definition   [KW-0413]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Enzyme and pathway databases
SABIO-RK: Q15125
Other
GenomeRNAi: 10682
PRO: PR:Q15125