RASA2 - Ras GTPase-activating protein 2 - human protein (Function)
 
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Protein
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References

 
RASA2 »  Ras GTPase-activating protein 2
 
Protein also known as:  GTPase-activating protein 1m (GAP1m).
Gene name:  RASA2
Entry whose protein(s) existence is based on evidence at protein level
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1 24 2
GENE REF ISO

Function

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Overview 
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).  
  • CuratedUniProtKB
GO molecular function 
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Ras GTPase activator activitydefinition[GO:0005099] silver  
  • IBARefGenome
GO biological process 
Intracellular signal transductiondefinition[GO:0035556] silver  
  • IEAInterPro 2 GO
Negative regulation of Ras protein signal transductiondefinition[GO:0046580] silver  
  • IBARefGenome
Positive regulation of Ras GTPase activitydefinition[GO:0032320] silver  
  • IBARefGenome
Signal transductiondefinition[GO:0007165]  
2
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
MAPK signaling pathway  hsa04010+5922  
 

Keywords

Molecular function 
GTPase activation  definition   [KW-0343]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 5922
PRO: PR:Q15283