TOMM20 - Mitochondrial import receptor subunit TOM20 homolog - human protein (Function)
 
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Protein
Gene
References

 
TOMM20 »  Mitochondrial import receptor subunit TOM20 homolog
 
Protein also known as:  Mitochondrial 20 kDa outer membrane protein.
Gene name:  TOMM20
Family name: Tom20
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 31 1
GENE REF ISO

Function

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Overview 
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).  
  • CuratedUniProtKB
GO molecular function 
P-P-bond-hydrolysis-driven protein transmembrane transporter activitydefinition[GO:0015450]  
1
  • IDAHGNC
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
  • IPIHGNC
Unfolded protein bindingdefinition[GO:0051082]  
1
  • IDAHGNC
GO biological process 
Protein targeting to mitochondriondefinition[GO:0006626]  
1
  • IDAHGNC
Protein transmembrane transportdefinition[GO:0071806]  
1
  • IDAGOC
Pathways 
According to Reactome, this protein belongs to the following pathway:
Mitochondrial protein import  REACT_118595  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: TOMM20
GenomeRNAi: 9804
PRO: PR:Q15388