CNGA2 - Cyclic nucleotide-gated olfactory channel - human protein (Function)
 
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CNGA2 »  Cyclic nucleotide-gated olfactory channel
 
Protein also known as:  Cyclic nucleotide-gated cation channel 2.
Gene name:  CNGA2
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.  
  • CuratedUniProtKB
GO molecular function 
Calmodulin bindingdefinition[GO:0005516]  
  • IEAUniProtKB KW
cAMP bindingdefinition[GO:0030552]  
  • IEAUniProtKB KW
cGMP bindingdefinition[GO:0030553] silver  
  • IBARefGenome
Intracellular cGMP activated cation channel activitydefinition[GO:0005223] silver  
  • IBARefGenome
Voltage-gated potassium channel activitydefinition[GO:0005249] silver  
  • IBARefGenome
GO biological process 
Phototransduction, visible lightdefinition[GO:0007603] silver  
  • IBARefGenome
Potassium ion transmembrane transportdefinition[GO:0071805] silver  
  • IBARefGenome
Regulation of ion transmembrane transportdefinition[GO:0034765] silver  
  • IBARefGenome
Regulation of membrane potentialdefinition[GO:0042391] silver  
  • IBARefGenome
Regulation of transportdefinition[GO:0051049] silver  
  • IBARefGenome
Sensory perception of smelldefinition[GO:0007608] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Olfaction  definition   [KW-0552]
Sensory transduction  definition   [KW-0716]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Ligand-gated ion channel  definition   [KW-1071]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links