SGCA - Alpha-sarcoglycan - human protein (Function)
 
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Protein
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SGCA »  Alpha-sarcoglycan  (Alpha-SG)
 
Protein also known as:  50 kDa dystrophin-associated glycoprotein (50DAG).
Gene name:  SGCA
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAInterPro 2 GO
GO biological process 
Muscle contractiondefinition[GO:0006936] silver  
  • IEAInterPro 2 GO
Muscle organ developmentdefinition[GO:0007517] silver  
  • IEAInterPro 2 GO
Pathways 
According to KEGG, this protein belongs to the following pathways:
Arrhythmogenic right ventricular cardiomyopathy (ARVC)  hsa05412+6442  
Dilated cardiomyopathy  hsa05414+6442  
Hypertrophic cardiomyopathy (HCM)  hsa05410+6442  
Viral myocarditis  hsa05416+6442  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SGCA
GenomeRNAi: 6442
PRO: PR:Q16586