ARHGAP31 - Rho GTPase-activating protein 31 - human protein (Function)
 
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Protein
Gene
References

 
ARHGAP31 »  Rho GTPase-activating protein 31
 
Protein also known as:  Cdc42 GTPase-activating protein.
Gene name:  ARHGAP31
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration.  
2
  • CuratedUniProtKB
GO molecular function 
GTPase activator activitydefinition[GO:0005096] silver  
  • IEAOrtholog Compara
SH3 domain bindingdefinition[GO:0017124] silver  
  • IEAOrtholog Compara
GO biological process 
Positive regulation of GTPase activitydefinition[GO:0043547] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Rho GTPase cycle  REACT_11051  
 

Keywords

Molecular function 
GTPase activation  definition   [KW-0343]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ARHGAP31
GenomeRNAi: 57514
PRO: PR:Q2M1Z3