ARID4B - AT-rich interactive domain-containing protein 4B - human protein (Function)
 
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ARID4B »  AT-rich interactive domain-containing protein 4B  (ARID domain-containing protein 4B)
 
Protein also known as:  Histone deacetylase complex subunit SAP180.
Gene name:  ARID4B
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.  
2
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
Transcription regulatory region DNA bindingdefinition[GO:0044212]  
1
  • RefGenome
GO biological process 
Establishment of Sertoli cell barrierdefinition[GO:0097368] silver  
1
  • Ortholog Compara
Histone H3-K9 trimethylationdefinition[GO:0036124] silver  
1
  • Ortholog Compara
Histone H4-K20 trimethylationdefinition[GO:0034773] silver  
1
  • Ortholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
1
  • Ortholog Compara
Regulation of gene expression by genetic imprintingdefinition[GO:0006349] silver  
1
  • Ortholog Compara
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357]  
1
  • RefGenome
Spermatogenesisdefinition[GO:0007283] silver  
1
  • Ortholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • UniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathways:
HDACs deacetylate histones  REACT_263923  
NoRC negatively regulates rRNA expression  REACT_263965  
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ARID4B
GenomeRNAi: 51742
PRO: PR:Q4LE39