EPHA10 - Ephrin type-A receptor 10 - human protein (Function)
 
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EPHA10 »  Ephrin type-A receptor 10   [ EC 2.7.10.1 ]
 
Gene name:  EPHA10
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 26 3
GENE REF ISO

Function

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Overview 
Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.  
2
  • UniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • UniProtKB KW
Ephrin receptor activitydefinition[GO:0005003] silver  
1
  • InterPro 2 GO
Isoforms  Iso 2 and Iso 3   Protein bindingdefinition[GO:0005515]  
2
  • IntAct
  • UniProtKB
Isoform  Iso 2   Transmembrane-ephrin receptor activitydefinition[GO:0005005]  
1
  • UniProtKB
GO biological process 
Isoform  Iso 2   Ephrin receptor signaling pathwaydefinition[GO:0048013]  
1
  • GOC
Peptidyl-tyrosine phosphorylationdefinition[GO:0018108]  
3
  • InterPro 2 GO
  • EC 2 GO
  • UniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.10.1: ATP + a [protein]-L-tyrosine ADP + a [protein]-L-tyrosine phosphate.  
1
  • UniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathways:
EPH-ephrin mediated repulsion of cells  REACT_264198  
EPH-Ephrin signaling  REACT_264068  
EPHA-mediated growth cone collapse  REACT_264548  
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Receptor  definition   [KW-0675]
Transferase  definition   [KW-0808]
Tyrosine-protein kinase  definition   [KW-0829]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: EPHA10
GenomeRNAi: 284656
PRO: PR:Q5JZY3