ABCC10 - Multidrug resistance-associated protein 7 - human protein (Function)
 
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Protein
Gene
References

 
ABCC10 »  Multidrug resistance-associated protein 7
 
Protein also known as:  ATP-binding cassette sub-family C member 10.
Gene name:  ABCC10
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 36 2
GENE REF ISO

Function

 show evidences
Overview 
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.  
2
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the atp-binding cassette (abc) superfamily  3.A.1.208.31  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
ATPase activity, coupled to transmembrane movement of substancesdefinition[GO:0042626] silver  
  • IEAInterPro 2 GO
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
  • IEAInterPro 2 GO
Pathways 
According to KEGG, this protein belongs to the following pathway:
ABC transporters  hsa02010+89845  
According to Reactome, this protein belongs to the following pathway:
ABC-family proteins mediated transport  REACT_15480  
 

Biophysicochemical properties

Kinetic parameters
KM 57.8 uM for 17-beta-estradiol 17-(beta-D-glucuronide) (at 37 degrees Celsius)
Vmax 20 pmol/min/mg enzyme toward 17-beta-estradiol 17-(beta-D-glucuronide) (at 37 degrees Celsius)

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ABCC10
GenomeRNAi: 89845
PRO: PR:Q5T3U5