HHAT - Protein-cysteine N-palmitoyltransferase HHAT - human protein (Function)
 
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Protein
Gene
References

 
HHAT »  Protein-cysteine N-palmitoyltransferase HHAT   [ EC 2.3.1.- ]
 
Protein also known as:  Melanoma antigen recognized by T-cells 2 (MART-2).
Gene name:  HHAT
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling (By similarity). May bind GTP.  
1
  • UniProtKB
GO molecular function 
GTP bindingdefinition[GO:0005525]  
1
  • UniProtKB KW
Palmitoyltransferase activitydefinition[GO:0016409] silver  
1
  • Ortholog Compara
GO biological process 
Multicellular organismal developmentdefinition[GO:0007275]  
1
  • UniProtKB KW
Positive regulation of protein targeting to mitochondriondefinition[GO:1903955]  
1
  • ParkinsonsUK-UCL
Protein palmitoylationdefinition[GO:0018345] silver  
1
  • Ortholog Compara
Smoothened signaling pathwaydefinition[GO:0007224] silver  
1
  • Ortholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathways:
Hedgehog ligand biogenesis  REACT_264605  
Hh ligand biogenesis disease  REACT_263883  
 

Keywords

Molecular function 
Acyltransferase  definition   [KW-0012]
Developmental protein  definition   [KW-0217]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 55733
PRO: PR:Q5VTY9