UBE2U - Ubiquitin-conjugating enzyme E2 U - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
UBE2U »  Ubiquitin-conjugating enzyme E2 U   [ EC 6.3.2.19 ]
 
Protein also known as:  Ubiquitin carrier protein U.
Gene name:  UBE2U
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 10 2
GENE REF ISO

Function

 show evidences
Overview 
Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Acid-amino acid ligase activitydefinition[GO:0016881] silver  
  • IEAInterPro 2 GO
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
GO biological process 
Protein ubiquitinationdefinition[GO:0016567]  
  • IEAUniPathway
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 6.3.2.19: ATP + ubiquitin + protein lysine AMP + diphosphate + protein N-ubiquityllysine.  
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathway:
Ubiquitin mediated proteolysis  hsa04120+148581  
According to Reactome, this protein belongs to the following pathway:
Antigen processing: Ubiquitination & Proteasome degradation  REACT_75842  
 

Keywords

Biological process 
Ubl conjugation pathway  definition   [KW-0833]
Molecular function 
Ligase  definition   [KW-0436]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 148581
PRO: PR:Q5VVX9