ARID2 - AT-rich interactive domain-containing protein 2 - human protein (Function)
 
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ARID2 »  AT-rich interactive domain-containing protein 2  (ARID domain-containing protein 2)
 
Protein also known as:  Zinc finger protein with activation potential.
Gene name:  ARID2
Entry whose protein(s) existence is based on evidence at protein level
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1 44 2
GENE REF ISO

Function

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Overview 
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.  
1
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
  • IEAUniProtKB KW
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Chromatin modificationdefinition[GO:0016568]  
  • IEAUniProtKB KW
Nucleosome disassemblydefinition[GO:0006337]  
1
  • IDABHF-UCL
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
  • IEAUniProtKB KW
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Chromatin regulator  definition   [KW-0156]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ARID2
GenomeRNAi: 196528
PRO: PR:Q68CP9