PLEKHA7 - Pleckstrin homology domain-containing family A member 7 - human protein (Function)
 
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PLEKHA7 »  Pleckstrin homology domain-containing family A member 7  (PH domain-containing family A member 7)
 
Gene name:  PLEKHA7
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site.  
1
  • CuratedUniProtKB
GO molecular function 
Delta-catenin bindingdefinition[GO:0070097]  
1
  • IDAUniProtKB
GO biological process 
Epithelial cell-cell adhesiondefinition[GO:0090136]  
1
  • IMPUniProtKB
Zonula adherens maintenancedefinition[GO:0045218]  
1
  • IMPUniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 144100
PRO: PR:Q6IQ23