PNCK - Calcium/calmodulin-dependent protein kinase type 1B - human protein (Function)
 
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Protein
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PNCK »  Calcium/calmodulin-dependent protein kinase type 1B
 
Gene name:  PNCK
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1 (By similarity).  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Calmodulin bindingdefinition[GO:0005516]  
  • IEAUniProtKB KW
Calmodulin-dependent protein kinase activitydefinition[GO:0004683]  
  • IEAEC 2 GO
GO biological process 
Protein phosphorylationdefinition[GO:0006468] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.17: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
It is regulated in the following manner
Activated by Ca(2+)/calmodulin (By similarity).  
  • CuratedUniProtKB
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GenomeRNAi: 139728
PRO: PR:Q6P2M8
Chemistry
GuidetoPHARMACOLOGY: 2172