KCNV1 - Potassium voltage-gated channel subfamily V member 1 - human protein (Function)
 
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Protein
Gene
References

 
KCNV1 »  Potassium voltage-gated channel subfamily V member 1
 
Protein also known as:  Neuronal potassium channel alpha subunit HNKA.
Gene name:  KCNV1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 26 1
GENE REF ISO

Function

 show evidences
Overview 
Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.  
3
  • UniProtKB
GO molecular function 
Delayed rectifier potassium channel activitydefinition[GO:0005251]  
1
  • RefGenome
Ion channel inhibitor activitydefinition[GO:0008200]  
1
  • PINC
Potassium channel regulator activitydefinition[GO:0015459]  
1
  • PINC
GO biological process 
Potassium ion transmembrane transportdefinition[GO:0071805]  
1
  • RefGenome
Potassium ion transportdefinition[GO:0006813]  
1
  • PINC
Protein homooligomerizationdefinition[GO:0051260] silver  
1
  • InterPro 2 GO
Regulation of ion transmembrane transportdefinition[GO:0034765]  
1
  • UniProtKB KW
Pathways 
According to Reactome, this protein belongs to the following pathway:
Voltage gated Potassium channels  REACT_75770  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: KCNV1
GenomeRNAi: 27012
PRO: PR:Q6PIU1