VHLL - Von Hippel-Lindau-like protein - human protein (Function)
 
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Protein
Gene
References

 
VHLL »  Von Hippel-Lindau-like protein  (VLP)
 
Gene name:  VHLL
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Functions as a dominant-negative VHL to serve as a protector of HIFalpha.  
2
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
Note 
Has little or no E3 ubiquitin ligase activity as it lacks the alpha domain required for nucleating the multiprotein E3 ubiquitin ligase complex.  
1
  • UniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 391104
PRO: PR:Q6RSH7