KCNT2 - Potassium channel subfamily T member 2 - human protein (Function)
 
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KCNT2 »  Potassium channel subfamily T member 2
 
Protein also known as:  Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1.
Gene name:  KCNT2
Entry whose protein(s) existence is based on evidence at protein level
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1 34 4
GENE REF ISO

Function

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Overview 
Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.  
2
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the voltage-gated ion channel (vic) superfamily  1.A.1.3.6  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Calcium-activated potassium channel activitydefinition[GO:0015269] silver  
  • IBARefGenome
Voltage-gated potassium channel activitydefinition[GO:0005249] silver  
  • IBARefGenome
GO biological process 
Potassium ion transmembrane transportdefinition[GO:0071805] silver  
  • IBARefGenome
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: KCNT2
GenomeRNAi: 343450
PRO: PR:Q6UVM3
Chemistry
GuidetoPHARMACOLOGY: 386