WDR82 - WD repeat-containing protein 82 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
WDR82 »  WD repeat-containing protein 82
 
Protein also known as:  Protein TMEM113.
Gene name:  WDR82
Family name: WD repeat SWD2
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 19 1
GENE REF ISO

Function

 show evidences
Overview 
Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.  
3
  • CuratedUniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682] silver  
  • IEAOrtholog Compara
Contributes to histone methyltransferase activity (H3-K4 specific)definition[GO:0042800]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
3
  • IPIUniProtKB
GO biological process 
Histone H3-K4 methylationdefinition[GO:0051568]  
1
  • IDAUniProtKB
Caution 
The gene encoding this protein shares one overlapping exon with TMEM113.  
  • CuratedUniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 80335
PRO: PR:Q6UXN9