NPSR1 - Neuropeptide S receptor - human protein (Function)
 
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NPSR1 »  Neuropeptide S receptor
 
Protein also known as:  G-protein coupled receptor for asthma susceptibility.
Gene name:  NPSR1
Entry whose protein(s) existence is based on evidence at transcript level
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1 49 9
GENE REF ISO

Function

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Overview 
May be active in signaling pathway in an autocrine or paracrine fashion in several tissues. Receptor for neuropeptide S, it may mediate its action, such as inhibitory effects, on cell growth. Involved in pathogenesis of asthma and other IgE-mediated diseases.  
2
  • CuratedUniProtKB
GO molecular function 
Vasopressin receptor activitydefinition[GO:0005000] silver  
  • IEAInterPro 2 GO
Pathways 
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
Note 
Only isoforms with 7 transmembrane topology (isoform 1, isoform 3 and isoform 4) are transported into the plasma membrane in transfected cells, while the truncated ones retain intracellular compartments.  
  • CuratedUniProtKB
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Neuropeptide_S_receptor
GenomeRNAi: 387129
PRO: PR:Q6W5P4
Chemistry
GuidetoPHARMACOLOGY: 302