TMPRSS11A - Transmembrane protease serine 11A - human protein (Function)
 
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TMPRSS11A »  Transmembrane protease serine 11A   [ EC 3.4.21.- ]
 
Protein also known as:  Epidermal type-II transmembrane serine protease.
Gene name:  TMPRSS11A
Family name: Peptidase S1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.  
  • CuratedUniProtKB
GO molecular function 
Serine-type endopeptidase activitydefinition[GO:0004252] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell cycledefinition[GO:0007049]  
  • IEAUniProtKB KW
Proteolysisdefinition[GO:0006508]  
  • IEAUniProtKB KW
Enzymatic activity 
 
More information is available from:
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
Molecular function 
Hydrolase  definition   [KW-0378]
Protease  definition   [KW-0645]
Serine protease  definition   [KW-0720]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 339967
PRO: PR:Q6ZMR5