ZBTB49 - Zinc finger and BTB domain-containing protein 49 - human protein (Function)
 
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ZBTB49 »  Zinc finger and BTB domain-containing protein 49
 
Protein also known as:  Zinc finger protein 509.
Gene name:  ZBTB49
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription.  
2
  • UniProtKB
GO molecular function 
Metal ion bindingdefinition[GO:0046872]  
1
  • UniProtKB KW
Sequence-specific DNA bindingdefinition[GO:0043565]  
1
  • UniProtKB
Transcription coactivator bindingdefinition[GO:0001223]  
1
  • UniProtKB
Transcription factor bindingdefinition[GO:0008134]  
1
  • UniProtKB
GO biological process 
Cell cycle arrestdefinition[GO:0007050]  
1
  • UniProtKB
Negative regulation of cell proliferationdefinition[GO:0008285]  
1
  • UniProtKB
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
1
  • UniProtKB
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 166793
PRO: PR:Q6ZSB9