CAPN12 - Calpain-12 - human protein (Function)
 
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Protein
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CAPN12 »  Calpain-12   [ EC 3.4.22.- ]
 
Protein also known as:  Calcium-activated neutral proteinase 12 (CANP 12).
Gene name:  CAPN12
Family name: Peptidase C2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Calcium-regulated non-lysosomal thiol-protease (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAInterPro 2 GO
Calcium-dependent cysteine-type endopeptidase activitydefinition[GO:0004198] silver  
  • IBARefGenome
GO biological process 
Proteolysisdefinition[GO:0006508] silver  
  • IBARefGenome
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.4.22.-: Broad endopeptidase specificity.  
  • CuratedUniProtKB
 
More information is available from:
 

Keywords

Molecular function 
Hydrolase  definition   [KW-0378]
Protease  definition   [KW-0645]
Thiol protease  definition   [KW-0788]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 147968
PRO: PR:Q6ZSI9