NEK10 - Serine/threonine-protein kinase Nek10 - human protein (Function)
 
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NEK10 »  Serine/threonine-protein kinase Nek10   [ EC 2.7.11.1 ]
 
Protein also known as:  Never in mitosis A-related kinase 10 (NimA-related protein kinase 10).
Gene name:  NEK10
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Protein kinase activitydefinition[GO:0004672]  
1
  • IDAUniProtKB
Protein serine/threonine kinase activitydefinition[GO:0004674]  
  • IEAUniProtKB KW
Protein tyrosine kinase activitydefinition[GO:0004713] silver  
  • IEAInterPro 2 GO
GO biological process 
Peptidyl-tyrosine phosphorylationdefinition[GO:0018108]  
  • IEAInterPro 2 GO
Positive regulation of MAP kinase activitydefinition[GO:0043406]  
1
  • IMPUniProtKB
Positive regulation of protein autophosphorylationdefinition[GO:0031954]  
1
  • IDAUniProtKB
Protein phosphorylationdefinition[GO:0006468]  
1
  • IDAUniProtKB
Regulation of cell cycle G2/M phase transitiondefinition[GO:1902749]  
1
  • IMPUniProtKB
Regulation of ERK1 and ERK2 cascadedefinition[GO:0070372]  
1
  • IMPUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
It requires the following cofactor
Magnesium (By similarity).  
  • CuratedUniProtKB
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 152110
PRO: PR:Q6ZWH5