GTF2H5 - General transcription factor IIH subunit 5 - human protein (Function)
 
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Protein
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References

 
GTF2H5 »  General transcription factor IIH subunit 5
 
Protein also known as:  TFIIH basal transcription factor complex TTD-A subunit.
Gene name:  GTF2H5
Family name: TFB5
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Component of the TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell.  
1
  • CuratedUniProtKB
GO biological process 
Nucleotide-excision repairdefinition[GO:0006289]  
1
  • IMPMGI
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
  • IEAUniProtKB KW
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathways:
Basal transcription factors  hsa03022+404672  
Nucleotide excision repair  hsa03420+404672  
 

Keywords

Biological process 
DNA damage  definition   [KW-0227]
DNA repair  definition   [KW-0234]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: GTF2H5
GenomeRNAi: 404672
PRO: PR:Q6ZYL4