OLIG3 - Oligodendrocyte transcription factor 3 - human protein (Function)
 
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Protein
Gene
References

 
OLIG3 »  Oligodendrocyte transcription factor 3  (Oligo3)
 
Protein also known as:  Class E basic helix-loop-helix protein 20 (bHLHe20).
Gene name:  OLIG3
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.  
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
  • IEAUniProtKB KW
Protein dimerization activitydefinition[GO:0046983] silver  
  • IEAInterPro 2 GO
RNA polymerase II transcription corepressor activitydefinition[GO:0001106] silver  
  • IEAOrtholog Compara
GO biological process 
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122] silver  
  • IEAOrtholog Compara
Spinal cord motor neuron cell fate specificationdefinition[GO:0021520] silver  
  • IEAOrtholog Compara
Spinal cord motor neuron migrationdefinition[GO:0097476] silver  
  • IEAOrtholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 167826
PRO: PR:Q7RTU3