ATG9A - Autophagy-related protein 9A - human protein (Function)
 
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Protein
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References

 
ATG9A »  Autophagy-related protein 9A
 
Protein also known as:  APG9-like 1.
Gene name:  ATG9A
Family name: ATG9
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.  
1
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
GO biological process 
Autophagic vacuole assemblydefinition[GO:0000045]  
1
  • IMPMGI
Innate immune responsedefinition[GO:0045087] silver  
  • IEAOrtholog Compara
Protein localization to Golgi apparatusdefinition[GO:0034067] silver  
  • IEAOrtholog Compara
Protein transportdefinition[GO:0015031]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Autophagy  definition   [KW-0072]
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ATG9A
GenomeRNAi: 79065
PRO: PR:Q7Z3C6