TRPM1 - Transient receptor potential cation channel subfamily M member 1 - human protein (Function)
 
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Protein
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References

 
TRPM1 »  Transient receptor potential cation channel subfamily M member 1
 
Protein also known as:  Long transient receptor potential channel 1 (LTrpC1).
Gene name:  TRPM1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Cation channel essential for the depolarizing photoresponse of retinal ON bipolar cells. It is part of the GRM6 signaling cascade. May play a role in metastasis suppression (By similarity). May act as a spontaneously active, calcium-permeable plasma membrane channel.  
3
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the transient receptor potential ca(2+) channel (trp-cc) family  1.A.4.5.2  
GO molecular function 
Calcium channel activitydefinition[GO:0005262]  
1
  • IDAUniProtKB
GO biological process 
Calcium ion transport into cytosoldefinition[GO:0060402]  
1
  • IDAUniProtKB
Cellular response to light stimulusdefinition[GO:0071482]  
1
  • IMPUniProtKB
G-protein coupled glutamate receptor signaling pathwaydefinition[GO:0007216]  
1
  • IMPUniProtKB
Retinal rod cell developmentdefinition[GO:0046548] silver  
  • IEAOrtholog Compara
Transportdefinition[GO:0006810]  
1
  • TASPINC
Visual perceptiondefinition[GO:0007601]  
1
  • IMPUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
TRP channels  REACT_169333  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Sensory transduction  definition   [KW-0716]
Transport  definition   [KW-0813]
Vision  definition   [KW-0844]
Molecular function 
Ion channel  definition   [KW-0407]
Ligand-gated ion channel  definition   [KW-1071]
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: TRPM1
GenomeRNAi: 4308
PRO: PR:Q7Z4N2
Chemistry
GuidetoPHARMACOLOGY: 493